Archives: “Archives”

Stefan Feske, MD

https://www.coltonconsortium.org/directory/stefan-feske-md/

Vice Chair for Research, Department of Pathology, NYU Grossman School of Medicine / NYU Langone Health Jeffrey Bergstein Professor of Medicine, Department of Pathology, NYU Grossman School of Medicine / NYU […]

Golnaz Vahedi, PhD

https://www.coltonconsortium.org/directory/golnaz-vahedi-phd/

Professor, Department of Genetics, Perelman School of Medicine, University of Pennsylvania Dr. Golnaz Vahedi is a Professor of Genetics at the Perelman School of Medicine, University of Pennsylvania, Co-Director of […]

E. John Wherry, PhD

https://www.coltonconsortium.org/directory/e-john-wherry-phd/

Chair & Richard and Barbara Schiffrin President’s Distinguished Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Director, Colton Consortium for Autoimmunity Director, Colton […]

Amy Baxter, PhD

https://www.coltonconsortium.org/directory/amy-baxter-phd/

Research Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Dr. Amy Baxter is a Research Assistant Professor of Systems Pharmacology and Translational […]

Asaf Madi, PhD

https://www.coltonconsortium.org/directory/asaf-madi-phd/

Professor, Tel Aviv UniversityGray Faculty of Medical and Health Sciences (Cancer Biology and Immunology) Dr. Asaf Madi completed his PhD in computational immunology at Tel Aviv University, followed by postdoctoral […]

Andrew Wells, PhD

https://www.coltonconsortium.org/directory/andrew-wells-phd/

Professor, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania Dr. Andrew Wells is Professor of Pathology and Laboratory Medicine at the Perelman School of Medicine, […]

Carrie Lucas, PhD

https://www.coltonconsortium.org/directory/carrie-lucas-phd/

Associate Professor, Department of Immunobiology, Department of Immunobiology, Yale School of Medicine, Yale University Associate Director of Human and Translational Immunology, Department of Immunobiology, Yale School of Medicine, Yale University […]

Joseph Craft, MD

https://www.coltonconsortium.org/directory/joseph-craft-md/

Paul B. Beeson Professor of Medicine (Rheumatology), Department of Internal Medicine (Rheumatology, Allergy & Immunology), Yale School of Medicine, Yale University Professor of Immunobiology, Department of Immunobiology, Yale School of […]

The Role and Mechanism of Aberrant Dendritic Cell Function in Autoimmunity

https://www.coltonconsortium.org/projects/the-role-and-mechanism-of-aberrant-dendritic-cell-function-in-autoimmunity/

Identifying a novel molecular regulator of tolerogenic dendritic cell function, this project uncovers how its loss triggers spontaneous multiorgan autoimmunity and exacerbates lupus — revealing a clinically relevant pathway in immune tolerance.

Developing New Mode-of-Action Calcineurin Inhibitors for Acute Colitis Therapeutics

https://www.coltonconsortium.org/projects/developing-new-mode-of-action-calcineurin-inhibitors-for-acute-colitis-therapeutics/

Targeting the calcineurin-NFAT protein-protein interaction rather than enzyme active sites, this project develops a novel class of inhibitors to treat steroid-refractory ulcerative colitis with fewer side effects.