- Professor, Tel Aviv University
Gray Faculty of Medical and Health Sciences (Cancer Biology and Immunology)
Dr. Asaf Madi completed his PhD in computational immunology at Tel Aviv University, followed by postdoctoral training at Harvard Medical School, Brigham and Women’s Hospital, and the Broad Institute under the mentorship of Aviv Regev and Vijay Kuchroo.
Dr. Madi’s laboratory studies the molecular and cellular mechanisms that regulate immune responses in cancer and autoimmune diseases. His group combines experimental and computational approaches — including single-cell and spatial genomics, molecular biology, and advanced computational methods — to investigate how immune cell states, interactions, and signaling networks shape disease progression and therapeutic responses.
Current research focuses on the mechanisms driving immune dysregulation, loss of tolerance, and chronic inflammation across cancer immunotherapy, autoimmune diseases, and inflammatory disorders, with the goal of identifying pathways that improve diagnosis and treatment. In parallel, the lab develops artificial intelligence and computational pathology approaches to extract biological and clinical insights from tissue imaging and genomic data. By integrating high-dimensional data with functional and translational immunology, the Madi lab aims to uncover fundamental principles of immune regulation and advance precision medicine for immune-mediated diseases.
