- Research Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania
Dr. Amy Baxter is a Research Assistant Professor of Systems Pharmacology and Translational Therapeutics and Director of Research and Development for Immune Health at the Perelman School of Medicine, University of Pennsylvania. She received her BA and MSci from the University of Cambridge and her DPhil from the University of Oxford, where her doctoral work examined T cell responses in chronic viral infection.
Dr. Baxter’s research focuses on the biology of T cell exhaustion and dysfunction in chronic immune activation — a state first characterized in viral infection and cancer that is increasingly recognized as a feature of autoimmune disease. Working closely with the Wherry laboratory, she has applied high-dimensional immune profiling and single-cell sequencing to define exhausted T cell states across human cohorts and to identify candidate biomarkers and therapeutic targets relevant to autoimmune indications.
As Director of R&D for Immune Health, Dr. Baxter leads the operational science behind Penn’s Immune Health program, translating cutting-edge immune profiling assays into platforms that can be deployed across patient cohorts. She is a key collaborator within the Institute for Immunology and Immune Health and the Penn Colton Center, where her work supports the development of immune monitoring frameworks for clinical and translational autoimmunity research.