https://www.coltonconsortium.org/news/penn-colton-center-launches-two-new-centers-of-excellence-to-fast-track-autoimmune-treatments/
The Penn Colton Center has launched two new Centers of Excellence — HIT-AI, focused on AI-driven drug repurposing, and CREATE, pioneering mRNA therapies — to accelerate next-generation autoimmune diagnostics and treatments.
https://www.coltonconsortium.org/news/nyu-langone-study-identifies-precision-approach-to-dialing-down-harmful-t-cell-activity-in-autoimmune-disease/
A Colton-supported NYU Langone study has engineered a bispecific antibody that precisely silences harmful T cell activity — showing promise across mouse models of type 1 diabetes, hepatitis, and multiple sclerosis.
https://www.coltonconsortium.org/news/yale-study-overturns-decades-of-dogma-t-cells-live-in-the-healthy-brain-via-a-gut-fat-brain-axis/
A Colton-supported Yale study published in Nature has shown for the first time that T cells live in the healthy brain, traveling there from the gut via a newly discovered gut-fat-brain axis.
https://www.coltonconsortium.org/news/building-the-future-of-immune-health-highlights-from-the-2025-penn-colton-center-symposium/
The 2025 Penn Colton Center Symposium convened 150+ experts to explore breakthroughs in immune health and spotlight Penn's leadership, future headquarters, and innovations in autoimmunity research and precision medicine.
https://www.coltonconsortium.org/news/yale-study-finds-skin-injury-can-trigger-food-allergies-via-a-skin-gut-immune-connection/
A Colton-supported Yale study published in Science Immunology shows that skin injury can trigger food allergies via a skin-gut immune connection — offering a new explanation for the link between eczema and food allergy.
https://www.coltonconsortium.org/news/new-hope-for-sjgrens-disease-patients-nyu-study-links-calcium-signaling-and-t-cell-dysfunction-to-the-condition/
A Colton-supported NYU study published in Science Translational Medicine has identified impaired regulatory T cells as a key driver of Sjögren's disease — and found a promising existing drug as a potential therapy.
https://www.coltonconsortium.org/news/tau-colton-centers-2024-grant-recipients-tackle-autoimmune-disease-across-nine-interdisciplinary-projects/
Tel Aviv University's Colton Center has awarded nine interdisciplinary research grants in 2024, funding projects that explore autoimmune disease from organ-on-a-chip platforms to the role of stress and psychological factors in disease flare-ups.
https://www.coltonconsortium.org/news/penn-medicines-colton-center-is-driving-the-next-immunotherapy-revolution-this-time-for-autoimmune-disease/
Penn Medicine's Colton Center is leading a new wave of precision immunotherapy for autoimmune disease — from CAAR T cell therapy for pemphigus to immune profiling tools that could one day cure these conditions.
https://www.coltonconsortium.org/news/yales-colton-center-awards-750k-to-seven-autoimmune-disease-research-projects/
Yale's Colton Center for Autoimmunity has awarded $750,000 to seven faculty-led projects advancing research into autoimmune and allergic diseases, with funding, mentorship, and commercialization support.
https://www.coltonconsortium.org/news/lupus-flare-ups-strongly-linked-to-specific-bacterial-growth-in-gut/
NYU Langone researchers have linked lupus flare-ups to blooms of a specific gut bacterium, opening a potential path to probiotic and dietary treatments less toxic than current immunosuppressive therapies.