Announcements
June 6, 2024

TAU Colton Center’s 2024 Grant Recipients Tackle Autoimmune Disease Across Nine Interdisciplinary Projects

Tel Aviv University’s Colton Center for Autoimmunity has announced nine grant-winning research teams for 2024, spanning a broad range of scientific and clinical approaches to autoimmune disease. The awards include development grants of $200,000, Eureka pilot grants of $50,000, and a special emergency grant category introduced following the events of October 7, 2023, to study the relationship between acute stress and autoimmune disease.

The two development grant recipients are pursuing particularly novel platforms: Prof. Ben Maoz is developing a “Mini-Me-on-a-Chip” — a microfluidic organ-on-a-chip system for modeling autoimmune disease — while Dr. Maayan Gal and Dr. Ehud Zigmond are exploring a new class of calcineurin inhibitors as a potential treatment for acute colitis.

The emergency grant awardees are examining how psychological stress interacts with immune function — studying its effects on multiple sclerosis relapse risk and on autoimmune exacerbation more broadly, reflecting a growing area of scientific interest in the mind-body dimensions of immune disease.

The Eureka grants — organized around the themes of Autoimmunity & Ecology and Autoimmunity & Mind — fund projects ranging from extracellular vesicles as biomarkers for lupus, to postpartum Hashimoto’s thyroiditis, to the neurological and psychological dimensions of Crohn’s disease. The interdisciplinary teams draw researchers from TAU, Sheba Medical Center, Tel Aviv Medical Center, Bar-Ilan University, and the Weizmann Institute of Science, as well as one collaborator from Yale.

AnnouncementsAutoimmune EpidemiologyBiological & MechanisticBiomarker DiscoveryData-Driven & QuantitativeExperimental Platforms & ModelsIn Vitro ModelsMachine Learning & AINeuro-Immune InteractionsOrganoidsPopulation & Patient-CenteredTherapeutic DevelopmentTranslational & ClinicalAutoimmunity in PregnancyCrohn's DiseaseCross-Cutting & Special PopulationsEndocrine DiseasesGastrointestinal DiseasesHashimoto's ThyroiditisMultiple SclerosisNeurologic DiseasesOtherSystemic DiseasesSystemic Lupus Erythematosus (SLE)Tel Aviv University

Featured Experts

Katsuo Kurabayashi, PhD

Katsuo Kurabayashi, PhD

Colton Consortium Member

Department Chair, Mechanical and Aerospace Engineering, NYU Tandon School of Engineering
Carla R. Nowosad, PhD

Carla R. Nowosad, PhD

Colton Consortium Member

Assistant Professor, Department of Pathology, NYU Grossman School of Medicine / NYU Langone Health
Jun Wang, PhD

Jun Wang, PhD

Colton Consortium Member

Associate Professor, Department of Pathology, NYU Grossman School of Medicine / NYU Langone Health

Featured Publications

The multiple roles of gamma interferon in intraepithelial T cell-villous enterocyte interactions in active celiac disease

bioRxiv [Preprint]
Johnson, JE; Agrawal, K; Al-Lamki, RS; Zhang, F; Wang, X; Liburd Jr, S; Tobiasova, Z; Rodriguez, L; Martins, AJ; Sefik, E; Flavell, RA; Robert, ME; Pober, JS September 2024
Adaptive ImmunityBiological & MechanisticCytokine SignalingExperimental Platforms & ModelsHuman CohortsIn Vitro ModelsInnate ImmunitySingle Cell TechnologiesT Cell BiologyCeliac DiseaseGastrointestinal DiseasesYale University

The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour

Nature
Yoshida, TM; Nguyen, M; Zhang, L; Lu, BY; Zhu, B; Murray, KN; Mineur, YS; Zhang, C; Xu, D; Lin, E; Luchsinger, J; Bhatta, S; Waizman, DA; Coden, ME; Ma, Y; Israni-Winger, K; Russo, A; Wang, H; Song, W; Al Souz, J; Zhao, H; Craft, JE; Picciotto, MR; Grutzendler, J; Distasio, M; Palm, NW; Hafler, DA; Wang, A May 2025
Adaptive ImmunityAnimal ModelsBioinformaticsBiological & MechanisticData-Driven & QuantitativeExperimental Platforms & ModelsHuman CohortsMicrobiome–Immune InteractionsNeuro-Immune InteractionsSingle Cell TechnologiesT Cell BiologyOtherYale University
From the Consortium

Related News

What a "Silenced" Chromosome Can Tell Us About Autoimmunity
In the Media Research Findings
June 25, 2026

What a "Silenced" Chromosome Can Tell Us About Autoimmunity

Penn Colton Center researcher Montserrat Anguera reveals how B cells maintain X chromosome inactivation, and how its breakdown drives lupus, offering new insight into female-biased autoimmune disease and treatment targets.

Yale News Spotlights the Colton Center as a Key Driver of Autoimmune Innovation at Yale Ventures
In the Media
March 5, 2026

Yale News Spotlights the Colton Center as a Key Driver of Autoimmune Innovation at Yale Ventures

A Yale News feature on Yale Ventures' five accelerator funds highlights the Colton Center for Autoimmunity's growing role in translating autoimmune research into startups, licenses, and real-world therapies.

Yale Researchers Use Machine Learning Tool to Improve Personalized Immunotherapy Design
Research Findings
February 25, 2026

Yale Researchers Use Machine Learning Tool to Improve Personalized Immunotherapy Design

A Colton-supported Yale study has produced ImmunoStruct, a machine learning model that improves personalized cancer vaccine design by incorporating the 3D structure of immune-activating peptides — now licensed to a Yale spinout.