Publication 2
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Yale Study Discovers a Second Pathway for Gut Antibody Production — With Implications for Vaccine Design
https://www.coltonconsortium.org/news/yale-study-discovers-a-second-pathway-for-gut-antibody-production-with-implications-for-vaccine-design/A Colton-supported Yale study has uncovered a second pathway for gut IgA antibody production, revealing a built-in immune backup system with significant implications for mucosal vaccine design.
Yale Researchers Identify Two New Therapeutic Targets for Fibrotic Diseases Like Scleroderma and Lupus
https://www.coltonconsortium.org/news/yale-researchers-identify-two-new-therapeutic-targets-for-fibrotic-diseases-like-scleroderma-and-lupus/Two Yale studies have identified a promising new antibody therapy and a previously unknown signaling pathway as potential treatments for fibrotic autoimmune diseases including scleroderma, lupus, and graft-versus-host disease.
Colton Consortium Sponsors 2025 FASEB Autoimmunity Conference
https://www.coltonconsortium.org/news/colton-consortium-sponsors-2025-faseb-autoimmunity-conference/The Colton Consortium sponsored the 2025 FASEB Autoimmunity Conference in Niagara Falls, a leading international forum dedicated to advancing autoimmune research and fostering collaboration among scientists and clinicians worldwide.
Yale’s Colton Center for Autoimmunity Awards Nearly $1M to Nine Research Projects in 2025
https://www.coltonconsortium.org/news/yales-colton-center-for-autoimmunity-awards-nearly-1m-to-nine-research-projects-in-2025/Yale's Colton Center for Autoimmunity has selected nine researchers for nearly $1 million in 2025 funding, backing projects that apply AI, nanoparticles, and novel biologics to autoimmune disease.
NYU Langone Study Identifies Precision Approach to Dialing Down Harmful T Cell Activity in Autoimmune Disease
https://www.coltonconsortium.org/news/nyu-langone-study-identifies-precision-approach-to-dialing-down-harmful-t-cell-activity-in-autoimmune-disease/A Colton-supported NYU Langone study has engineered a bispecific antibody that precisely silences harmful T cell activity — showing promise across mouse models of type 1 diabetes, hepatitis, and multiple sclerosis.
Yale Study Overturns Decades of Dogma: T Cells Live in the Healthy Brain Via a Gut-Fat-Brain Axis
https://www.coltonconsortium.org/news/yale-study-overturns-decades-of-dogma-t-cells-live-in-the-healthy-brain-via-a-gut-fat-brain-axis/A Colton-supported Yale study published in Nature has shown for the first time that T cells live in the healthy brain, traveling there from the gut via a newly discovered gut-fat-brain axis.
Yale Study Finds Skin Injury Can Trigger Food Allergies Via a Skin-Gut Immune Connection
https://www.coltonconsortium.org/news/yale-study-finds-skin-injury-can-trigger-food-allergies-via-a-skin-gut-immune-connection/A Colton-supported Yale study published in Science Immunology shows that skin injury can trigger food allergies via a skin-gut immune connection — offering a new explanation for the link between eczema and food allergy.
Yale Scientists Use Lupus Antibody to Unlock Immune Response Against Hard-to-Treat Cancers
https://www.coltonconsortium.org/news/yale-scientists-use-lupus-antibody-to-unlock-immune-response-against-hard-to-treat-cancers/Yale researchers have found that a lupus-related antibody can penetrate "cold" tumors and activate immune responses — offering a promising new approach to treating glioblastoma and other hard-to-treat cancers.
New Hope for Sjögren’s Disease Patients: NYU Study Links Calcium Signaling and T Cell Dysfunction to the Condition
https://www.coltonconsortium.org/news/new-hope-for-sjgrens-disease-patients-nyu-study-links-calcium-signaling-and-t-cell-dysfunction-to-the-condition/A Colton-supported NYU study published in Science Translational Medicine has identified impaired regulatory T cells as a key driver of Sjögren's disease — and found a promising existing drug as a potential therapy.