Archives: “Archives”

Developing a Molecular Microscope for Celiac Disease

Developing an IFNγ-based molecular microscope to assess celiac disease activity and response to treatment without relying solely on diagnostic biopsies.

Generation and Validation of a New Humanized Mouse Model, A Surrogate for Human Celiac Disease

Developing and validating a humanized MISTRG6 mouse model that accurately replicates human immune responses to gluten for celiac disease research and drug development.

The multiple roles of gamma interferon in intraepithelial T cell-villous enterocyte interactions in active celiac disease

T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B

Microbiome research in autoimmune and immune-mediated inflammatory diseases: lessons, advances and unmet needs

Opportunities for improving biopsy and non-biopsy-based diagnosis of celiac disease

Elucidating the role of autoreactive T cells and B cells in autoimmune hepatitis

Differences in disease characteristics and treatment exposures between paediatric and adult-onset inflammatory bowel disease using a registry-based cohort

Yale Study Discovers a Second Pathway for Gut Antibody Production — With Implications for Vaccine Design

A Colton-supported Yale study has uncovered a second pathway for gut IgA antibody production, revealing a built-in immune backup system with significant implications for mucosal vaccine design.

Yale’s Colton Center for Autoimmunity Awards Nearly $1M to Nine Research Projects in 2025

Yale's Colton Center for Autoimmunity has selected nine researchers for nearly $1 million in 2025 funding, backing projects that apply AI, nanoparticles, and novel biologics to autoimmune disease.