A Colton-supported Yale study has produced ImmunoStruct, a machine learning model that improves personalized cancer vaccine design by incorporating the 3D structure of immune-activating peptides — now licensed to a Yale spinout.
A Colton-supported Yale study has uncovered a second pathway for gut IgA antibody production, revealing a built-in immune backup system with significant implications for mucosal vaccine design.
Two Yale studies have identified a promising new antibody therapy and a previously unknown signaling pathway as potential treatments for fibrotic autoimmune diseases including scleroderma, lupus, and graft-versus-host disease.
Yale's Colton Center for Autoimmunity has selected nine researchers for nearly $1 million in 2025 funding, backing projects that apply AI, nanoparticles, and novel biologics to autoimmune disease.
The Colton Center for Autoimmunity at Yale University presented a showcase on Colton-funded research featuring investigators from across the Consortium.
A Colton-supported Yale study published in Nature has shown for the first time that T cells live in the healthy brain, traveling there from the gut via a newly discovered gut-fat-brain axis.
A Colton-supported Yale study published in Science Immunology shows that skin injury can trigger food allergies via a skin-gut immune connection — offering a new explanation for the link between eczema and food allergy.
Yale researchers have found that a lupus-related antibody can penetrate "cold" tumors and activate immune responses — offering a promising new approach to treating glioblastoma and other hard-to-treat cancers.
Yale's Colton Center for Autoimmunity has selected eleven faculty-led projects for 2024 funding, supporting breakthrough research into lupus, asthma, allergies, and other autoimmune diseases — with mentorship and commercialization support included.
Yale's Colton Center for Autoimmunity has awarded $750,000 to seven faculty-led projects advancing research into autoimmune and allergic diseases, with funding, mentorship, and commercialization support.
