At the 2025 Yale Innovation Summit, the Colton Center for Autoimmunity hosted a showcase of Colton-funded research projects from across the Consortium, highlighting the translational potential of cutting-edge autoimmune science. The session brought together researchers from the University of Pennsylvania, New York University, and Yale University to present work spanning novel therapeutics, biologics, and diagnostics — several of which have already attracted commercial interest or launched startup companies.
Presenters included Professor Taku Kambayashi and Professor Michela Locci of the University of Pennsylvania, Dr. Jun Wang of New York University, and Dr. James Hansen of Yale University.
Watch the full Colton Center for Autoimmunity Showcase from the 2025 Yale Innovation Summit
Featured Experts

Sara Baier, MEd
Associate Director of External Relations, Colton Consortium for Autoimmunity
Colton Center for Autoimmunity, Perelman School of Medicine, University of Pennsylvania
Jennifer Gillen, MBA
Administrative Manager, Judith & Stewart Colton Center for Autoimmunity (NYU)
Department of Medicine, NYU Grossman School of Medicine / NYU Langone Health, New York University
Kenneth Hassinger
Director of Finance, Colton Consortium for Autoimmunity
Colton Center for Autoimmunity, Perelman School of Medicine, University of PennsylvaniaFeatured Projects

The Role of Glycosylation in Inflammatory Bowel Disease
Investigating how foreign sugar modifications on anti-TNF biologics trigger immune responses in pediatric IBD patients, this project aims to personalize biologic therapy selection and inform safer drug design.

A Data-Driven Framework for Predicting and Managing Flares in Inflammatory Bowel Disease
Combining machine learning with microbiome and metabolomic data from 4,000+ IBD patients, this project develops tools to predict disease flares, identify therapeutic targets, and enable personalized flare prevention.
Featured Publications
Tolebrutinib in nonrelapsing secondary progressive multiple sclerosis
Trajectory of beta cell function and insulin clearance in stage 2 type 1 diabetes: natural history and response to teplizumab
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