Archives: “Multi-omics Integration”

Amy Baxter, PhD

https://www.coltonconsortium.org/directory/amy-baxter-phd/

Research Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Dr. Amy Baxter is a Research Assistant Professor of Systems Pharmacology and Translational […]

Aristotelis Tsirigos, PhD

https://www.coltonconsortium.org/directory/aristotelis-tsirigos-phd/

Professor, Department of Medicine, NYU Grossman School of Medicine / NYU Langone Health Professor, Department of Pathology, NYU Grossman School of Medicine / NYU Langone Health Co-Director, Division of Precision […]

Joel Babdor, PhD

https://www.coltonconsortium.org/directory/joel-babdor-phd/

Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Dr. Joel Babdor is an Assistant Professor of Systems Pharmacology and Translational Therapeutics at […]

Caroline R. Bartman, PhD

https://www.coltonconsortium.org/directory/caroline-r-bartman-phd/

Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Dr. Caroline Bartman is an Assistant Professor of Systems Pharmacology and Translational Therapeutics at […]

Joseph Craft, MD

https://www.coltonconsortium.org/directory/joseph-craft-md/

Paul B. Beeson Professor of Medicine (Rheumatology), Department of Internal Medicine (Rheumatology, Allergy & Immunology), Yale School of Medicine, Yale University Professor of Immunobiology, Department of Immunobiology, Yale School of […]

Early Detection and Diagnosis of Autoimmune Diseases Using Foundation AI Models

https://www.coltonconsortium.org/projects/early-detection-and-diagnosis-of-autoimmune-diseases-using-foundation-ai-models/

Applying self-supervised AI to multi-modal electronic health records — integrating clinical notes, labs, and imaging — this project builds scalable diagnostic models to detect autoimmune diseases earlier and more precisely.

The Epidermis as a Novel Therapeutic Target in Pemphigus Vulgaris

https://www.coltonconsortium.org/projects/the-epidermis-as-a-novel-therapeutic-target-in-pemphigus-vulgaris/

By profiling genetic and molecular drivers of pemphigus vulgaris across patient skin and blood, this project uncovers genotype-driven inflammatory loops and actionable targets for personalized therapy.

A Data-Driven Framework for Predicting and Managing Flares in Inflammatory Bowel Disease

https://www.coltonconsortium.org/projects/a-data-driven-framework-for-predicting-and-managing-flares-in-inflammatory-bowel-disease/

Combining machine learning with microbiome and metabolomic data from 4,000+ IBD patients, this project develops tools to predict disease flares, identify therapeutic targets, and enable personalized flare prevention.

High-Throughput Center for AutoImmune Therapeutic Discovery (HIT-AI)

https://www.coltonconsortium.org/projects/high-throughput-center-for-autoimmune-therapeutic-discovery-hit-ai/

Systematically identifying and validating repurposed FDA-approved drugs for over 160 autoimmune diseases using AI, knowledge graphs, and high-throughput experimental screening.

Profiling Urine Methylation in Lupus Nephritis

https://www.coltonconsortium.org/projects/profiling-urine-methylation-in-lupus-nephritis/

Identifying urine DNA methylation signatures as a non-invasive biomarker for lupus nephritis class and disease progression.