Associate Professor, Department of Pediatrics (Rheumatology), Children’s Hospital of Philadelphia / University of Pennsylvania Dr. Scott Canna is Associate Professor of Pediatrics in the Division of Rheumatology at the Children’s […]
Associate Professor, Department of Immunobiology, Department of Immunobiology, Yale School of Medicine, Yale University Associate Director of Human and Translational Immunology, Department of Immunobiology, Yale School of Medicine, Yale University […]
Assistant Professor, Department of Medicine (Hematology-Oncology), Perelman School of Medicine, University of Pennsylvania Dr. Daria Babushok is an Assistant Professor of Medicine in the Division of Hematology-Oncology at the Perelman […]
Building a fluorescence-based cellular screening platform to identify small molecules targeting mutant UBA1, this project addresses an acute unmet need in VEXAS syndrome and lays groundwork for broader rheumatic disease therapies.
Identifying a novel molecular regulator of tolerogenic dendritic cell function, this project uncovers how its loss triggers spontaneous multiorgan autoimmunity and exacerbates lupus — revealing a clinically relevant pathway in immune tolerance.
By profiling genetic and molecular drivers of pemphigus vulgaris across patient skin and blood, this project uncovers genotype-driven inflammatory loops and actionable targets for personalized therapy.
Developing a bioavailable DNAseIL3 biologic to degrade pathogenic autoantibodies and treat lupus and related autoimmune diseases.
Developing and validating a humanized MISTRG6 mouse model that accurately replicates human immune responses to gluten for celiac disease research and drug development.
Identifying the autoantigens and T cell clonotypes driving immune attack in aplastic anemia to enable more precise diagnostics and targeted therapies.
