https://www.coltonconsortium.org/news/nyu-research-reveals-the-double-life-of-key-immune-checkpoint-protein-pd-1/
A Colton-supported NYU study published in Science Immunology has discovered that the immune checkpoint protein PD-1 functions as a dimer — a finding that could transform drug design for both cancer and autoimmune disease.
https://www.coltonconsortium.org/news/penn-medicines-colton-center-is-driving-the-next-immunotherapy-revolution-this-time-for-autoimmune-disease/
Penn Medicine's Colton Center is leading a new wave of precision immunotherapy for autoimmune disease — from CAAR T cell therapy for pemphigus to immune profiling tools that could one day cure these conditions.
https://www.coltonconsortium.org/news/lupus-flare-ups-strongly-linked-to-specific-bacterial-growth-in-gut/
NYU Langone researchers have linked lupus flare-ups to blooms of a specific gut bacterium, opening a potential path to probiotic and dietary treatments less toxic than current immunosuppressive therapies.
https://www.coltonconsortium.org/news/tel-aviv-university-opens-israels-first-autoimmune-disease-research-center/
Tel Aviv University's Colton Center for Autoimmunity joins a four-university consortium dedicated to finding cures for over 100 autoimmune diseases through big data analytics, multidisciplinary research, and international collaboration.
https://www.coltonconsortium.org/news/penn-medicine-launches-colton-center-for-autoimmunity-with-10-million-gift/
Penn Medicine's new Colton Center for Autoimmunity unites the university's immunology research and patient care programs, joining NYU and Yale in a shared effort to advance autoimmune disease diagnosis and treatment.
https://www.coltonconsortium.org/news/yales-colton-center-for-autoimmunity-awards-2022-grants-to-six-innovative-research-projects/
Yale's Colton Center for Autoimmunity has awarded 2022 grants to six projects spanning lupus, multiple sclerosis, pediatric OCD, and systemic sclerosis — all targeting new diagnostics, therapies, or disease mechanisms.
https://www.coltonconsortium.org/news/nyu-langone-joins-58m-nih-partnership-to-accelerate-autoimmune-disease-research/
NYU Langone's Colton-backed Division of Rheumatology is taking a leading role in the NIH's $58 million AMP AIM program, driving research into lupus, psoriatic disease, Sjögren's disease, and the microbiome.
https://www.coltonconsortium.org/news/yale-researchers-use-skin-as-a-window-into-autoimmune-disease-and-a-path-to-better-treatments/
Yale Medicine Magazine profiles Colton-funded researchers using skin as a diagnostic and therapeutic entry point into autoimmune disease — from scleroderma antibody therapy to cancer-triggered bullous pemphigoid.
https://www.coltonconsortium.org/news/how-lupus-antibodies-sabotage-a-key-enzyme-and-what-it-means-for-treating-kidney-disease/
Colton-supported NYU researchers have found that autoantibodies can physically inactivate a key enzyme in over half of lupus nephritis patients — a non-genetic mechanism that could serve as a future biomarker and therapeutic target.
https://www.coltonconsortium.org/news/nyu-langones-colton-center-funds-seven-new-autoimmune-pilot-projects-from-lupus-to-myasthenia-gravis/
NYU Langone's Colton Center has funded seven new autoimmune pilot projects for 2019 — targeting myasthenia gravis, rheumatoid arthritis, and lupus — while earlier grants advance toward clinical diagnostics and therapies.