https://www.coltonconsortium.org/directory/carrie-lucas-phd/
Associate Professor, Department of Immunobiology, Department of Immunobiology, Yale School of Medicine, Yale University Associate Director of Human and Translational Immunology, Department of Immunobiology, Yale School of Medicine, Yale University […]
https://www.coltonconsortium.org/directory/joseph-craft-md/
Paul B. Beeson Professor of Medicine (Rheumatology), Department of Internal Medicine (Rheumatology, Allergy & Immunology), Yale School of Medicine, Yale University Professor of Immunobiology, Department of Immunobiology, Yale School of […]
https://www.coltonconsortium.org/projects/spatial-dynamics-of-intestinal-b-cell-immunoreceptor-signaling-in-health-and-disease-ibd/
Using single-molecule imaging to visualize B cell receptor signaling across gut compartments, this project uncovers how intestinal B cell education breaks down in IBD, revealing new targets for therapeutic intervention.
https://www.coltonconsortium.org/projects/ai-simulated-in-silico-humans-a-new-paradigm-for-modeling-autoimmunity/
Building AI-powered digital avatars that simulate each patient's immune system to predict therapy response and accelerate precision immunotherapy development.
https://www.coltonconsortium.org/projects/noninvasive-skin-protein-assessment-to-guide-targeted-treatment-selection-in-inflammatory-skin-diseases/
Using DIPS, a non-invasive skin sampling technique, to build cytokine-based biomarker panels that predict biologic treatment response in psoriasis and atopic dermatitis.
https://www.coltonconsortium.org/projects/biomarker-discovery-for-early-prediction-of-autoimmunity-in-immunotherapy-patients-through-deep-immune-profiling-and-temporal-graph-convolutional-networks/
Using temporal graph machine learning and deep immune profiling to predict which cancer immunotherapy patients will develop autoimmune adverse events before they occur.
https://www.coltonconsortium.org/projects/autoantibodies-in-long-covid/
Investigating the autoimmune and immune dysregulation mechanisms underlying Long COVID to improve diagnosis, treatment, and biological understanding of persistent symptoms.
https://www.coltonconsortium.org/projects/targets-of-autoimmune-attack-in-acquired-aplastic-anemia/
Identifying the autoantigens and T cell clonotypes driving immune attack in aplastic anemia to enable more precise diagnostics and targeted therapies.
https://www.coltonconsortium.org/projects/an-integrative-multi-modal-approach-to-define-and-diagnose-pediatric-autoimmune-neurological-disorders/
Building the largest cerebrospinal fluid immune profile dataset in pediatric autoimmune neurological diseases to enable faster, more accurate diagnosis of MS and related conditions.
https://www.coltonconsortium.org/projects/a-cho-cell-based-surface-display-platform-for-comprehensive-serological-profiling/
Building a CHO cell surface display library of all human proteins to enable comprehensive, high-throughput autoantibody profiling across autoimmune diseases and vaccine responses.