Archives: “Archives”

Katalin Susztak, MD, PhD

https://www.coltonconsortium.org/directory/katalin-susztak-md-phd/

Professor, Department of Medicine, Perelman School of Medicine, University of Pennsylvania Dr. Katalin Susztak is a Professor of Medicine in the Division of Renal Electrolyte and Hypertension and Professor of […]

Joseph Craft, MD

https://www.coltonconsortium.org/directory/joseph-craft-md/

Paul B. Beeson Professor of Medicine (Rheumatology), Department of Internal Medicine (Rheumatology, Allergy & Immunology), Yale School of Medicine, Yale University Professor of Immunobiology, Department of Immunobiology, Yale School of […]

Daria Babushok, MD, PhD

https://www.coltonconsortium.org/directory/daria-babushok-md-phd/

Assistant Professor, Department of Medicine (Hematology-Oncology), Perelman School of Medicine, University of Pennsylvania Dr. Daria Babushok is an Assistant Professor of Medicine in the Division of Hematology-Oncology at the Perelman […]

Benjamin Abramoff, MD, MS

https://www.coltonconsortium.org/directory/benjamin-abramoff-md-ms/

Associate Professor, Department of Physical Medicine and Rehabilitation, Perelman School of Medicine, University of Pennsylvania Dr. Benjamin Abramoff is an Assistant Professor of Physical Medicine and Rehabilitation at the Perelman […]

Early Detection and Diagnosis of Autoimmune Diseases Using Foundation AI Models

https://www.coltonconsortium.org/projects/early-detection-and-diagnosis-of-autoimmune-diseases-using-foundation-ai-models/

Applying self-supervised AI to multi-modal electronic health records — integrating clinical notes, labs, and imaging — this project builds scalable diagnostic models to detect autoimmune diseases earlier and more precisely.

The Role and Mechanism of Aberrant Dendritic Cell Function in Autoimmunity

https://www.coltonconsortium.org/projects/the-role-and-mechanism-of-aberrant-dendritic-cell-function-in-autoimmunity/

Identifying a novel molecular regulator of tolerogenic dendritic cell function, this project uncovers how its loss triggers spontaneous multiorgan autoimmunity and exacerbates lupus — revealing a clinically relevant pathway in immune tolerance.

The Epidermis as a Novel Therapeutic Target in Pemphigus Vulgaris

https://www.coltonconsortium.org/projects/the-epidermis-as-a-novel-therapeutic-target-in-pemphigus-vulgaris/

By profiling genetic and molecular drivers of pemphigus vulgaris across patient skin and blood, this project uncovers genotype-driven inflammatory loops and actionable targets for personalized therapy.

Developing a Multi-parameter Prognostic Prediction Model for Disability Ranks and Progression of Patients with Multiple Sclerosis at the Early Stages of the Disease

https://www.coltonconsortium.org/projects/developing-a-multi-parameter-prognostic-prediction-model-for-disability-ranks-and-progression-of-patients-with-multiple-sclerosis-at-the-early-stages-of-the-disease/

Integrating clinical, imaging, and biological data from large real-world MS cohorts, this project builds a machine learning model to predict disability progression early and enable personalized treatment decisions.

Defining Endotypes in Hidradenitis Suppurativa to Improve Treatment

https://www.coltonconsortium.org/projects/defining-endotypes-in-hidradenitis-suppurativa-to-improve-treatment/

Using spatial transcriptomics to map distinct HS disease endotypes and identify targeted therapeutic strategies for this underserved inflammatory skin disease.

Developing a Non-Invasive Biomarker Test to Classify Lupus Nephritis

https://www.coltonconsortium.org/projects/developing-a-non-invasive-biomarker-test-to-classify-lupus-nephritis/

Identifying DNA methylation signatures in blood and urine as non-invasive biomarkers to classify lupus nephritis and guide treatment without repeated biopsies.