Decoding immunobiology through genetic errors of immunity
https://www.coltonconsortium.org/publications/decoding-immunobiology-through-genetic-errors-of-immunity/
Archives: “Precision Medicine”
Showing 61 - 70 of 72 posts
Description of a novel splice site variant in UBA1 gene causing VEXAS syndrome
https://www.coltonconsortium.org/publications/description-of-a-novel-splice-site-variant-in-uba1-gene-causing-vexas-syndrome/
Differences in disease characteristics and treatment exposures between paediatric and adult-onset inflammatory bowel disease using a registry-based cohort
https://www.coltonconsortium.org/publications/differences-in-disease-characteristics-and-treatment-exposures-between-paediatric-and-adult-onset-inflammatory-bowel-disease-using-a-registry-based-cohort/
A phase 3 trial of upadacitinib for giant-cell arteritis
https://www.coltonconsortium.org/publications/a-phase-3-trial-of-upadacitinib-for-giant-cell-arteritis/
A randomized, double-blind, placebo-controlled trial of abatacept for the treatment of relapsing, non-severe granulomatosis with polyangiitis
https://www.coltonconsortium.org/publications/a-randomized-double-blind-placebo-controlled-trial-of-abatacept-for-the-treatment-of-relapsing-non-severe-granulomatosis-with-polyangiitis/
Agent-based modeling for personalized prediction of an experimental immune response to immunotherapeutic antibodies
https://www.coltonconsortium.org/publications/agent-based-modeling-for-personalized-prediction-of-an-experimental-immune-response-to-immunotherapeutic-antibodies/
Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells
https://www.coltonconsortium.org/publications/chimeric-antigen-receptor-t-cells-against-the-ighv4-34-b-cell-receptor-specifically-eliminate-neoplastic-and-autoimmune-b-cells/
Yale Researchers Use Machine Learning Tool to Improve Personalized Immunotherapy Design
https://www.coltonconsortium.org/news/yale-researchers-use-machine-learning-to-improve-personalized-cancer-vaccine-design/A Colton-supported Yale study has produced ImmunoStruct, a machine learning model that improves personalized cancer vaccine design by incorporating the 3D structure of immune-activating peptides — now licensed to a Yale spinout.
A New Research Hub for Autoimmunity and Immune Health at Penn Medicine
https://www.coltonconsortium.org/news/a-new-research-hub-for-autoimmunity-and-immune-health-at-penn-medicine/Penn Medicine has opened a new research facility housing the Colton Center for Autoimmunity alongside immune health, vaccinology, and infectious disease teams — designed to accelerate breakthrough science through collaboration.
Inside the 2025 Colton Consortium Symposium: Driving Translational Research in Autoimmune Disease
https://www.coltonconsortium.org/news/inside-the-2025-colton-consortium-symposium-driving-translational-research-in-autoimmune-disease/Global leaders in autoimmune research gathered for the 2025 Colton Consortium Symposium last month, sharing breakthroughs from foundational science to translational therapies and forging collaborations to improve patient lives worldwide.