Archives: “Archives”

Showing 31 - 40 of 68 posts

Hajera Amatullah, PhD

https://www.coltonconsortium.org/directory/hajera-amatullah-phd/

Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania Dr. Hajera Amatullah is an Assistant Professor of Systems Pharmacology and Translational Therapeutics at […]

Jill P. Buyon, MD

https://www.coltonconsortium.org/directory/jill-p-buyon-md/

Sir Deryck and Lady Va Maughan Professor of Rheumatology, Department of Medicine, NYU Grossman School of Medicine / NYU Langone Health Director, Division of Rheumatology, NYU Grossman School of Medicine […]

Carrie Lucas, PhD

https://www.coltonconsortium.org/directory/carrie-lucas-phd/

Associate Professor, Department of Immunobiology, Department of Immunobiology, Yale School of Medicine, Yale University Associate Director of Human and Translational Immunology, Department of Immunobiology, Yale School of Medicine, Yale University […]

Joseph Craft, MD

https://www.coltonconsortium.org/directory/joseph-craft-md/

Paul B. Beeson Professor of Medicine (Rheumatology), Department of Internal Medicine (Rheumatology, Allergy & Immunology), Yale School of Medicine, Yale University Professor of Immunobiology, Department of Immunobiology, Yale School of […]

Cornelius Y. Taabazuing, PhD

https://www.coltonconsortium.org/directory/cornelius-y-taabazuing-phd/

Presidential Assistant Professor, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania Dr. Cornelius Taabazuing is a Presidential Assistant Professor in the Department of Biochemistry and Biophysics […]

Development of UBA1 Targeted Therapies in VEXAS Syndrome

https://www.coltonconsortium.org/projects/development-of-uba1-targeted-therapies-in-vexas-syndrome/

Building a fluorescence-based cellular screening platform to identify small molecules targeting mutant UBA1, this project addresses an acute unmet need in VEXAS syndrome and lays groundwork for broader rheumatic disease therapies.

Utilizing RNA Replicons as Immune Modulators for Systemic Lupus Erythematosus

https://www.coltonconsortium.org/projects/utilizing-rna-replicons-as-immune-modulators-for-systemic-lupus-erythematosus/

A self-replicating RNA platform delivers anti-inflammatory cytokines directly to the airways, offering targeted local immune suppression without systemic toxicity — a mechanistically distinct approach to treating lupus lung disease.

Developing New Mode-of-Action Calcineurin Inhibitors for Acute Colitis Therapeutics

https://www.coltonconsortium.org/projects/developing-new-mode-of-action-calcineurin-inhibitors-for-acute-colitis-therapeutics/

Targeting the calcineurin-NFAT protein-protein interaction rather than enzyme active sites, this project develops a novel class of inhibitors to treat steroid-refractory ulcerative colitis with fewer side effects.