Experimental Platforms & Models
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https://www.coltonconsortium.org/projects/developing-a-universal-therapy-for-inflammasomopathies/
Uncovering the mechanisms by which inflammasomes drive aberrant inflammation in humans to identify new therapeutic targets for autoinflammatory diseases and sepsis.
https://www.coltonconsortium.org/publications/the-multiple-roles-of-gamma-interferon-in-intraepithelial-t-cell-villous-enterocyte-interactions-in-active-celiac-disease/
https://www.coltonconsortium.org/publications/the-subfornical-organ-is-a-nucleus-for-gut-derived-t-cells-that-regulate-behaviour/
https://www.coltonconsortium.org/publications/trajectory-of-beta-cell-function-and-insulin-clearance-in-stage-2-type-1-diabetes-natural-history-and-response-to-teplizumab/
https://www.coltonconsortium.org/publications/transcription-factor-etv3-controls-the-tolerogenic-function-of-dendritic-cells/
You might also be interested in… Soluble urine activated leukocyte cell adhesion molecule is a strong predictor of lupus nephritis Rheumatology Chu, D; Schwartz, N; Ampudia, J; Guthridge, J; James, […]
https://www.coltonconsortium.org/publications/transcriptomic-profiling-after-b-cell-depletion-reveals-central-and-peripheral-immune-cell-changes-in-multiple-sclerosis/
https://www.coltonconsortium.org/publications/transmembrane-domain-driven-pd-1-dimers-mediate-t-cell-inhibition/
https://www.coltonconsortium.org/publications/vessel-wall-mri-in-giant-cell-arteritis-standardized-protocol-and-scoring-approach-developed-by-an-international-working-group/
https://www.coltonconsortium.org/publications/soluble-urine-activated-leukocyte-cell-adhesion-molecule-is-a-strong-predictor-of-lupus-nephritis/
https://www.coltonconsortium.org/publications/spatial-atlas-of-diabetic-kidney-disease-reveals-a-b-cell-rich-subgroup/
