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Autoantibodies in Long COVID

https://www.coltonconsortium.org/projects/autoantibodies-in-long-covid/

Investigating the autoimmune and immune dysregulation mechanisms underlying Long COVID to improve diagnosis, treatment, and biological understanding of persistent symptoms.

Targets of Autoimmune Attack in Acquired Aplastic Anemia

https://www.coltonconsortium.org/projects/targets-of-autoimmune-attack-in-acquired-aplastic-anemia/

Identifying the autoantigens and T cell clonotypes driving immune attack in aplastic anemia to enable more precise diagnostics and targeted therapies.

Penn/CHOP Immune Kidney Disease Collaboratory

https://www.coltonconsortium.org/projects/penn-chop-immune-kidney-disease-collaboratory/

Building a spatial single-cell atlas of healthy and diseased human kidneys to redefine immune-mediated kidney disease and identify precision diagnostic and therapeutic targets.

Profiling Urine Methylation in Lupus Nephritis

https://www.coltonconsortium.org/projects/profiling-urine-methylation-in-lupus-nephritis/

Identifying urine DNA methylation signatures as a non-invasive biomarker for lupus nephritis class and disease progression.