Archives: “Biological & Mechanistic”

Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants

https://www.coltonconsortium.org/publications/kidney-multiome-based-genetic-scorecard-reveals-convergent-coding-and-regulatory-variants/

LB1037 single-cell and spatial transcriptomics reveal elevated pro-inflammatory fibroblasts and hormonal activity in hidradenitis suppurativa

https://www.coltonconsortium.org/publications/lb1037-single-cell-and-spatial-transcriptomics-reveal-elevated-pro-inflammatory-fibroblasts-and-hormonal-activity-in-hidradenitis-suppurativa/

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

https://www.coltonconsortium.org/publications/longitudinal-gut-microbiome-analyses-and-blooms-of-pathogenic-strains-during-lupus-disease-flares/

Machine learning approach to single cell transcriptomic analysis of Sjogren’s disease reveals altered activation states of B and T lymphocytes

https://www.coltonconsortium.org/publications/machine-learning-approach-to-single-cell-transcriptomic-analysis-of-sjogrens-disease-reveals-altered-activation-states-of-b-and-t-lymphocytes/

Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation

https://www.coltonconsortium.org/publications/metabolic-coordination-between-skin-epithelium-and-type-17-immunity-sustains-chronic-skin-inflammation/

Microbiome research in autoimmune and immune-mediated inflammatory diseases: lessons, advances and unmet needs

https://www.coltonconsortium.org/publications/microbiome-research-in-autoimmune-and-immune-mediated-inflammatory-diseases-lessons-advances-and-unmet-needs/

Diabetes mellitus—progress and opportunities in the evolving epidemic

https://www.coltonconsortium.org/publications/diabetes-mellitus-progress-and-opportunities-in-the-evolving-epidemic/

Divergent ontogeny of tissue resident memory and tissue resident exhausted CD8+ T cells underlies distinct functional potential

https://www.coltonconsortium.org/publications/divergent-ontogeny-of-tissue-resident-memory-and-tissue-resident-exhausted-cd8-t-cells-underlies-distinct-functional-potential/

EGFR-STAT1 pathway drives fibrosis initiation in fibroinflammatory skin diseases

https://www.coltonconsortium.org/publications/egfr-stat1-pathway-drives-fibrosis-initiation-in-fibroinflammatory-skin-diseases/

Elucidating the role of autoreactive T cells and B cells in autoimmune hepatitis

https://www.coltonconsortium.org/publications/elucidating-the-role-of-autoreactive-t-cells-and-b-cells-in-autoimmune-hepatitis/