- Professor, Department of Chemistry, Yale School of Medicine, Yale University
- Professor, Department of Microbial Pathogenesis, Yale School of Medicine, Yale University
Dr. Jason Crawford is a Professor of Chemistry and of Microbial Pathogenesis at Yale School of Medicine, where his laboratory is based at the Institute of Biomolecular Design and Discovery. He received his PhD from Johns Hopkins University and completed a postdoctoral fellowship and Pathway to Independence Fellowship at Harvard Medical School.
Dr. Crawford’s research sits at the intersection of chemistry, microbiology, and immunology, with a focus on discovering and characterizing small molecule metabolites produced by bacteria that influence host-pathogen interactions, gut homeostasis, and disease. His laboratory investigates how microbial communities in the gut produce chemical signals that shape immune responses, modulate drug activity, and contribute to gastrointestinal cancers and infectious disease. Recent work has demonstrated how gut microbiota metabolism influences the activity of GPCR-targeted drugs and identified novel signaling and virulence pathways in clinically relevant bacterial pathogens.
Dr. Crawford’s research has been published in leading journals including Nature, Nature Chemistry, Nature Microbiology, Nature Reviews Microbiology, and Science, and he has established active collaborations across immunology, oncology, and pharmacology at Yale.