- Assistant Professor, Department of Medicine (Pulmonary, Allergy and Critical Care), Perelman School of Medicine, University of Pennsylvania
Dr. Jacob Brenner is an Assistant Professor of Medicine in the Division of Pulmonary, Allergy and Critical Care at the Perelman School of Medicine, University of Pennsylvania, and Associate Director of Penn’s Center for Targeted Therapeutics and Translational Nanomedicine (CT3N). He received his MD from Stanford University and completed fellowship training in pulmonary and critical care medicine at Penn.
The Brenner laboratory designs and engineers targeted drug delivery platforms — including lipid nanoparticles, red blood cell hitchhiking strategies, and antibody-targeted nanocarriers — to direct therapeutics precisely to the lung, vasculature, and other inflamed tissues. His group applies these platforms to acute and chronic inflammatory lung disease, with growing focus on autoimmune-associated interstitial lung disease and other immune-mediated pulmonary conditions.
Dr. Brenner is a Penn Colton Center pilot awardee and partners broadly across the Institute for Immunology and Immune Health, Penn’s nanomedicine community, and industry to translate engineered delivery platforms into early-phase clinical applications. His work positions Penn as a leader in tissue-targeted immunomodulation for autoimmune and inflammatory disease.