Areas of Focus:

Functional Genomics & CRISPRImmune ProfilingSingle Cell TechnologiesT Cell BiologyTherapeutic DevelopmentCross-Cutting & Special Populations
  • Assistant Professor, Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv Sourasky Medical Center, Tel Aviv University
  • Assistant Professor, Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences,  Dotan Center for Advanced Therapies, Tel Aviv University

Dr. Eric Shifrut is an Assistant Professor at Tel Aviv University and a Principal Investigator at Tel Aviv Sourasky Medical Center. He completed his graduate studies at the Weizmann Institute of Science, where he mapped the T cell receptor (TCR) repertoire in health and disease. For his postdoctoral training, he joined the laboratory of Alex Marson at UCSF, where he pioneered CRISPR discovery platforms to study primary human T cells.

Dr. Shifrut has co-authored 36 papers and 8 patents in the fields of immunology and cell therapy, with over 5,000 citations. His independent research program leverages these advances in CRISPR engineering to design best-in-class T cell therapies against cancer.

Projects

Featured Pilot Projects

Immunotherapy-Related Adverse Effects as Models for Fragile Tolerance in Humans
Project | Tel Aviv University

Immunotherapy-Related Adverse Effects as Models for Fragile Tolerance in Humans

Using cancer patients experiencing immunotherapy-triggered autoimmunity as a unique human model, this project uncovers the molecular and epigenetic mechanisms by which self-reactive T cells escape immune tolerance.