Areas of Focus:

Adaptive ImmunityAnimal ModelsB Cell BiologyBiological & MechanisticExperimental Platforms & ModelsImmune DevelopmentCross-Cutting & Special PopulationsRare Autoimmune DiseasesSystemic DiseasesSystemic Lupus Erythematosus (SLE)
  • Professor, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania

Dr. David Allman is a Professor of Pathology and Laboratory Medicine and Vice Chair for Faculty Development in the Department of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania. He received his BS from Penn State University and his PhD in Immunology from the University of Pennsylvania, completing postdoctoral training at the Fox Chase Cancer Center before joining the Penn faculty.

The Allman laboratory is internationally recognized for its work on the cellular and molecular mechanisms governing B lymphocyte development, plasma cell differentiation, and humoral immunity. The lab has made foundational contributions to understanding how transitional and marginal zone B cell subsets emerge from progenitors, how long-lived plasma cells are generated and maintained, and how nutrient-sensing pathways such as mTORC1 shape germinal center responses — insights directly relevant to autoimmune diseases in which dysregulated B cells and pathogenic autoantibodies drive tissue damage.

Dr. Allman is a longstanding member of the Penn Institute for Immunology and Immune Health and the Penn Colton Center for Autoimmunity, where his expertise in B cell biology informs collaborative efforts to develop B cell–directed therapies for systemic autoimmune diseases. As Vice Chair for Faculty Development, he plays a central role in mentoring the next generation of immunologists at Penn.