Areas of Focus:

Adaptive ImmunityAnimal ModelsBiological & MechanisticCytokine SignalingExperimental Platforms & ModelsHuman CohortsSingle Cell TechnologiesSpatial BiologyAllergic & Atopic DiseasesOther
  • Assistant Professor, Department of Dermatology, Yale School of Medicine, Yale University

Dr. Anna Eisenstein is an Assistant Professor of Dermatology at Yale School of Medicine and a board-certified dermatologist specializing in chronic inflammatory skin diseases. She completed her undergraduate studies at Middlebury College, received her MD and PhD from Boston University School of Medicine, and completed her dermatology residency and postdoctoral training at Yale.

During her postdoctoral research in the laboratory of Dr. Andrew Wang, Dr. Eisenstein established a novel mechanism of action of commonly used nonsteroidal anti-inflammatory drugs and demonstrated how these and other industrial xenobiotics contribute to the development of allergic disease. She also identified a new paradigm in allergy biology — termed remote priming — whereby antigen and adjuvant signals are spatially separated, published in Science Immunology in 2025.

In clinical practice, Dr. Eisenstein specializes in hidradenitis suppurativa, an understudied and debilitating skin condition with limited treatment options, and serves as Director of the Hidradenitis Suppurativa Clinic at Yale. Her broader research investigates how environmental factors influence inflammatory skin diseases, including atopic dermatitis and hidradenitis suppurativa.

Her research has been supported by Career Development Awards from the Dermatology Foundation and the National Institute of Allergy and Infectious Diseases (NIAID).

Projects

Featured Pilot Projects

Defining Endotypes in Hidradenitis Suppurativa to Improve Treatment
Project | Yale University

Defining Endotypes in Hidradenitis Suppurativa to Improve Treatment

Using spatial transcriptomics to map distinct HS disease endotypes and identify targeted therapeutic strategies for this underserved inflammatory skin disease.