- Director of Immune Health, Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania
Dr. Allison Greenplate is Director of Immune Health for the Institute for Immunology and Immune Health (I3H) at the Perelman School of Medicine, University of Pennsylvania. She earned her PhD from Vanderbilt University’s Department of Pathology, Microbiology and Immunology, and completed postdoctoral training at the University of Pennsylvania, where her work helped establish high-dimensional cytometry and single-cell immune profiling as core capabilities for translational immunology at Penn.
Dr. Greenplate’s scientific program centers on the application of mass cytometry, single-cell sequencing, and high-dimensional flow cytometry to define immune cell states across health and disease. She has contributed to landmark studies of immune dysregulation in COVID-19, melanoma immunotherapy, and a range of autoimmune conditions, and co-leads the Colton Moonshot Program, which brings systems immunology approaches to bear on understanding and stratifying autoimmune disease across the Penn Colton Center for Autoimmunity.
In her dual leadership roles, Dr. Greenplate oversees Immune Health — Penn’s flagship initiative to translate deep immune phenotyping into clinically actionable insights — and helps shape the strategic and operational direction of I3H. She is a central convener of cross-institutional collaborations across Penn, CHOP, and the Colton Consortium partner sites, and is widely recognized for translating complex immune data into discoveries that inform clinical decision-making.